INTRODUCTION Millions of women worldwide have safely terminated their pregnancies with medication since mifepristone — or RU was first introduced in the late s. Research in the past two decades has identified several highly effective regimens for early medical abortion with a success rate of 95 to 98 percent, consisting of 200 mg of mifepristone followed by 400 or 800 mcg of misoprostol. 1 Whether taken in a health center or at home by women themselves, the regimen using pills offers an option that many women prefer to surgical procedures such as manual vacuum aspiration or dilation and curettage (D&C). Because mifepristone is a registered abortion drug, its sale and use are not permitted inmost countries with restrictive abortion laws. In contrast, misoprostol is an anti-ulcer medication that is registered under various trade names in more than 85 countries, Research has found that misoprostol used alone is about 85 percent successful in inducing abortion when used as recommended. Although less effective alone than when combined with mifepristone, misoprostol offers a safe and accessible alternative for women who have no other option.